Combined pathology is a real problem for rational pharmacotherapy due to multiple organ damage.The need to affect simultaneously several pathogenesis processes leads to polypharmacy that can appear to be less effective, toxic and unacceptable in some time.For comorbid patients with long - term ongoing type 2 diabetes mellitus (T2DM), the problem of
The organization of the axonal cytoskeleton is a key determinant of the normal function of an axon, which is a long thin projection of a neuron.Under normal conditions two axonal cytoskeletal polymers, microtubules and neurofilaments, align longitudinally in axons and are interspersed in axonal cross-sections.However, in many neurotoxic and neurode
The systemic movement of Cucumber mosaic virus (CMV) in cucumber plants was analyzed.The structure that is translocated and its putative interactions with phloem components were analyzed in phloem exudate (PE) samples, which reflect sieve tubes stream composition.Rate zonal centrifugation and electron-microscopy analyses of PE from CMV-infected pla
I Ketut Andika Priastana Universitas Triatma Mulya, Badung, Bali, IndonesiaCorrespondence: I Ketut Andika PriastanaUniversitas Triatma Mulya, Badung, Bali, IndonesiaTel +6283114213804Email iketutandikapriastana@gmail.com Dear editorI have read the study of laguna 3hp dust collector Mirmosayyeb et al entitled “Comparison of Psychological
Deafness: Missed mutations raise risk of hearing loss A gene associated with hereditary hearing loss may play a greater role than previously recognized in age-related auditory impairment.Many cases of autosomal dominant non-syndromic hearing loss (ADNSHL) arise from defects in KCNQ4, a protein that maintains the cellular ionic conditions needed for